Making our ends meet: shared intention, goal adoption and the third-person perspective

Making our ends meet: shared intention, goal adoption and the third-person perspective

Mind reading (i.e. the ability to infer the mental state of another agent) is taken to be the main cognitive ability required to share an intention and to collaborate. In this paper, I argue that another cognitive ability is also necessary to collaborate: representing others’ and ones’ own goals from a third-person perspective (other-centred or allocentric representation of goals). I argue that...

Hypothalamic glucose sensing: making ends meet

The neuroendocrine system governs essential survival and homeostatic functions. For example, growth is needed for development, thermoregulation maintains optimal core temperature in a changing environment, and reproduction ensures species survival. Stress and immune responses enable an organism to overcome external and internal threats while the circadian system regulates arousal and sleep such...

Making ends meet: String unification and low-energy data.

A long-standing problem in string phenomenology has been the fact that the string unification scale disagrees with the GUT scale obtained by extrapolating low-energy data within the framework of the minimal supersymmetric standard model (MSSM). In this paper we examine several effects that may modify the minimal string predictions and thereby bring string-scale unification into agreement with l...

Making Ends Meet: Reconciling Eoholism and Animal Rights Individualism

Making Ends Meet: Chemically Mediated Circularization of Recombinant Proteins

A selective N→S acyl transfer reaction facilitates semi-synthesis of the plant cyclotide kalata B1 from a linear precursor peptide of bacterial origin, through simple appendage of N-terminal cysteine and a thiol-labile C-terminal Gly-Cys motif. This constitutes the first synthesis of a ribosomally derived circular miniprotein, without recourse to protein splicing elements.